https://www.annotate-a-thon.org/blog daily 0.75 2020-03-06 https://www.annotate-a-thon.org/home daily 1.0 2021-07-13 https://static1.squarespace.com/static/5e2a530f9a01410615de6ddf/t/5e2cbf868de4173c96627ca4/1579990924645/4627129042_ce82762b33.jpg Home - 4. Chlamydophila pneumoniae CWL029 AKA Chlamydia pneumoniae Phylum: Chlamydiae Class: Chlamydiia Order: Chlamydiales Family: Chlamydiaceae Gram Negative must infect another cell to reproduce. associated with pneumonia, asthma, bronchitis, respiratory infection, coronary heart disease, and atherosclerosis infects koalas 1,230,230 base pairs 1052 protein coding genes 397 genes without predicted function (36%). 317 possible enzymes RESEARCH Chlamydia pneumoniae and Lung Cancer: Epidemiologic Evidence Chronic Chlamydophila pneumoniae infection in lung cancer, a risk factor: a case–control study Chronic Chlamydophila pneumoniae infection in lung cancer, a risk factor: A case-control study https://static1.squarespace.com/static/5e2a530f9a01410615de6ddf/t/5e2cbdc6e2129124f027da98/1579990478314/photo1.jpg Home - 3. Mycoplasma fermentans lives on mucus membranes Phylum: Tenericutes Class: Mollicutes Order: Mycoplasmatales Family: Mycoplasmataceae Gram Positive no cell wall associated with arthritis, chronic fatigue, and Lyme disease. facultative anaerobe 1,004,014 base pairs 893 protein coding genes 433 genes without predicted function (46.5%). 243 possible enzymes In one study, Mycoplasma infections were present in 50.9% of esophageal cancer, 52.6% of lung cancer, 39.7% of breast cancer and 41% of glioma (tumor that occurs in the brain and spinal cord). RESEARCH Mycoplasma infections and different human carcinomas Mycoplasmas and Human prostate cancer: An exciting but cautionary note Persistent Exposure to Mycoplasma Induces Malignant Transformation of Human Prostate Cells https://static1.squarespace.com/static/5e2a530f9a01410615de6ddf/t/5e2cbc59ad322f7ef25ce52b/1579990202213/%22Fusobacterium+nucleatum+%28Gram+stain%29%22+by+mostly*harmless+is+licensed+under+CC+BY-NC+2.0 Home - 2. Fusobacterium nucleatum lives in human oral cavity Phylum: Fusobacteria Class: Fusobacterii Order: Fusobacteriales Family: Fusobacteriaceae Gram Negative non-motile plays a role in periodontal disease Anaerobic 2,174,500 base pairs 2067 protein coding genes 568 genes without predicted function (26.5%). 672 possible enzymes "Fusobacterium nucleatum (Gram stain)" by mostly*harmless is licensed under CC BY-NC 2.0 RESEARCH Fusobacterium nucleatum and colorectal cancer: A review. Human Microbiome Fusobacterium Nucleatum in Esophageal Cancer Tissue Is Associated with Prognosis Association between Fusobacterium nucleatum and colorectal cancer: Progress and future directions https://static1.squarespace.com/static/5e2a530f9a01410615de6ddf/t/5e2cbe56db9920627be45c11/1579990622904/Hpylori.jpg Home - Helicobacter pylori 26695 previously known as Campylobacter pylori Super Kingdom: Bacteria Phylum: Proteobacteria Class: Epsilonproteobacteria Order: Campylobacterales Family: Helicobacteraceae Gram Negative 3-8 flagella Likes pH of 2 or less. Aerobic 1,667,892 base pairs 1594 protein coding genes 361 genes without predicted function (22%). 532 possible enzymes RESEARCH Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk Helicobacter pylori and colorectal cancer—A bacterium going abroad? Helicobacter pylori and gastric cancer: a state of the art review https://static1.squarespace.com/static/5e2a530f9a01410615de6ddf/t/5e2a538f9bccd63beb7cd4b7/1562691481546/dog-6.jpg Home - Why Bacteria? For a novice annotator, Prokaryotic genes are easier to annotate than Eukaryotic genes. Bacteria genomes have no privacy rights. Bacteria genomes are small. Bacteria genomes do not have introns (non-coding DNA). No exons that can be combined in different ways to make different proteins, called isoforms. Bacteria outnumber your body cells 10 to 1. RESEARCH Bacteria and cancer: cause, coincidence or cure? A review Bacteria-cancer interactions: bacteria-based cancer therapy Viruses, bacteria, and parasites – oh my! a resurgence of interest in microbial-based therapy for cancer Molecules Produced by Gut Bacteria Could Help The Human Body Fight Cancer https://static1.squarespace.com/static/5e2a530f9a01410615de6ddf/t/5e2cbfd58de4173c96628cf2/1579991004930/440px-ChlamydiaTrachomatisEinschlussk%C3%B6rperchen.jpg Home - 5. Chlamydia trachomatis D/UW-3/CX Phylum: Chlamydiae Class: Chlamydiia Order: Chlamydiales Family: Chlamydiaceae Aerobic Gram Negative, but lacks a peptidoglycan cell wall Coccoid or Rod shape cannot synthesize its own ATP 4 million cases are diagnosed each year. 1,042,519 base pairs plus 7493 base pair plasmid 895 protein coding genes 261 genes without predicted function (28%). 292 possible enzymes RESEARCH Chlamydia trachomatis and invasive cervical cancer: A pooled analysis of the IARC multicentric case‐control study Chlamydia trachomatis and cancer Antibodies Against Chlamydia trachomatis and Ovarian Cancer Risk in Two Independent Populations https://www.annotate-a-thon.org/our-mission daily 0.75 2020-01-24 https://www.annotate-a-thon.org/team daily 0.75 2020-01-24 https://static1.squarespace.com/static/5e2a530f9a01410615de6ddf/t/5e2a5c1fcc136f7bfa6de146/1579834408882/Knappenberger.jpg Team - Lon Knappenberger Tobias Keene, D.D.S. Hailing from Richmond, Virginia, Dr. Tobias Keene brings a bit of unabashed Southern hospitality to all his patients. He moved to Washington, D.C. over thirty years ago as a freshman at Ivy College. Right after graduation, he attended World University’s School of Dentistry. Before opening Keene Dental in 1994, he worked for free clinics and some of the finest practices in the District. He is part of the 123 Dental Association and stays up-to-date on the latest dental discoveries. When not striving to keep his patients happy and healthy, he’s enjoys hiking with his family in Rock Creek Park. https://www.annotate-a-thon.org/get-involved daily 0.75 2020-01-24 https://www.annotate-a-thon.org/services daily 0.75 2020-03-13 https://static1.squarespace.com/static/5e2a530f9a01410615de6ddf/t/5e3f01e3120d25193d4308b1/1581970132438/WebLogo.png Important Information What do the colors mean? https://static1.squarespace.com/static/5e2a530f9a01410615de6ddf/t/5e3f033b2c1d2d7368fa7974/1581187905053/T-Coffee.png Important Information https://static1.squarespace.com/static/5e2a530f9a01410615de6ddf/t/5e3f053f4b6b8940ee7bff59/1581188420331/Translation-table-to-convert-from-a-three-base-codon-to-an-amino-acid-A-single-amino.png.jpeg Important Information Convert DNA sequence to Amino Acid Sequence. Amino acids also have chemical properties, such as polar, neutral, basic, acidic, or hydrophobic. Polar Amino Acid-able to participate in hydrogen bonding. Hydrophilic. Glycine (G), Serine (S), Threonine (T), Tyrosine (Y) and Cysteine (C). Neutral Polar Amino acid.- amide side chain do NOT produce basic solutions. , proton donor or proton acceptor, Hydrophilic, Asparagine (N) and glutamine (Q) Basic Amino acid -Polar, Raise pH., Hydrophilic, nitrogen side chains, proton acceptor, form positive charges. Lysine (K), Arginine (R) and Histidine (H). Acidic Amino acid-Polar, lower pH, Hydrophilic, Carboxylic side chain, proton donor, form negative charges. Aspartic Acid (D) and Glutamic acid (E). Hydrophobic amino acid-”water Fearing” found buried in the core of a protein. side chains composed mostly of carbon and hydrogen. Alanine (A) , Isoleucine ( I), Leucine (L), Methionine (M ), Phenylalanine ( F), Valine (V), Proline ( P) and Glycine (G). https://static1.squarespace.com/static/5e2a530f9a01410615de6ddf/t/5e40aa97fbfe4d4e87b11860/1581296289428/3qh7.pdb1-500.jpg Important Information Source: http://www.rcsb.org/structure/3QH7 https://www.annotate-a-thon.org/donate daily 0.75 2020-03-13 https://static1.squarespace.com/static/5e2a530f9a01410615de6ddf/t/5e6c0703931e6a27c2c17679/1584138009883/ACGT+logo.jpg Donate https://static1.squarespace.com/static/5e2a530f9a01410615de6ddf/t/5e6c07c60f431516e15516e1/1584138211634/2b9d2f04-6215-11ea-bfc6-0e938d7a7a5b.png Donate